Prolonged sinus tachycardia caused by human herpesvirus 6 (HHV6) encephalomyelitis after allogeneic bone marrow transplantation.
نویسندگان
چکیده
A 19-year-old man with Philadelphia chromosome-positive acute lymphoblastic leukemia received an allogeneic hematopoietic cell transplant with unrelated bone marrow. On day 20, the patient developed impaired consciousness and disorientation. Examination of the cerebrospinal fluid showed 2×10(4) copies/mL of HHV6B. HHV6 encephalitis was diagnosed, as had HHV6 myelitis based on symptoms that included lancinating pain/pruritus in the lower limbs and dysuria/dyschezia. Concurrently, he showed sinus tachycardia. Even after clearance of the HHV6 genome from the plasma and CSF was achieved by treatment with foscarnet, sinus tachycardia persisted for another 100 days. We suspected prolonged sinus tachycardia due to dysautonomia caused by HHV6 encephalomyelitis.
منابع مشابه
Human Herpes Virus 6 Encephalitis Following Bone Marrow Transplantation with Uncommon Magnetic Resonance Imaging Findings
Human Herpes Virus 6 (HHV6) is known to be commonly associated with encephalitis related to immunosuppression and transplantation, and to bone marrow transplantation (BMT) in particular.1 HHV-6 is known to be common in transplant recipients and lead to several clinical manifestations, such as encephalitis.1-4 HHV 6 encephalitis in patients with BMT is known as latent infection. The first such c...
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عنوان ژورنال:
- Internal medicine
دوره 51 10 شماره
صفحات -
تاریخ انتشار 2012